Pesto Chicken Pasta Casserole Recipe (2024)

Our Pesto Chicken Pasta Casserole is made with chicken, tomatoes, spinach, basil, pesto, and cheese. It comes together in just a few minutes and is the perfect weeknight family dinner.

Pesto Chicken Pasta Casserole Recipe (1)

When it comes to easy family dinners, this Pesto Chicken Pasta Casserole is one of our favorites!

We love pasta recipes!

My family would eat spaghetti once a week if I let them, so I thought I would switch up our regular pasta-night dish with a simple pasta casserole.

Related Recipe: If you love this Pesto Chicken Casserole be sure to try our Pink Sauce Chicken Pasta Bake!

Pesto Chicken Pasta Casserole Recipe (2)

How to Make Pesto Chicken Pasta Casserole:

First, you’ll need to cook your noodles. We use penne pasta in this pasta bake, but any kind would work.

We’ve tried it with bowtie and our kids loved that too!

  • In a large bowl, mix together all of the ingredients listed to assemble the casserole.
  • After you have mixed together the ingredients for the casserole, you spread them in a 9×13-inch baking dish.
  • Next, you sprinkle a delicious, cheesy crumb mixture on top and put it in the oven!

This chicken casserole with pasta recipe is extremely simple and takes no time at all to assemble!

Pesto Chicken Pasta Casserole Recipe (3)

Related recipe: If you like this casserole, you’ll love our Mom’s Easy Chicken and Broccoli Casserole and our Beef and Noodle Casserole.

Pro tips on making a Chicken Casserole with Pasta:

Used canned goods: This recipe can be simple if you choose to use canned tomatoes, Alfredo, and pesto sauce. It’s almost a dump and go recipe that tastes amazing!

However, you can definitely use homemade or your favorite version of any of those mentioned above if you like to use fresher ingredients.

Try our Homemade Alfredo Sauce from this recipe!

Cool Off Your Pasta:Make sure to rinse your pasta off in cold water after you boil it.

This will keep it from sticking together when you’re trying to mix it with your other casserole ingredients.

Our best advice is to dump your pasta into a straining bowl like this one. Then run cold water over your pasta for 2 minutes.

If you love this casserole you definitely need to try our Million Dollar Casserole Recipe, Easy Chicken and Noodle Casserole and our Chicken and Broccoli Alfredo Casserole!

Pesto Chicken Pasta Casserole Recipe (4)

Homemade Pesto Sauce for this Pesto Chicken Pasta Casserole Recipe:

We know not everyone loves pre-made pesto or Alfredo sauce, so using your own is totally fine. Here’s our favorite recipe for homemade pesto sauce:

  • 3 cups fresh basil leaves
  • 1 1/2 cups chopped walnuts
  • 4 cloves garlic, peeled
  • 1/4 cup grated parmesan cheese
  • 1 cup olive oil
  • Salt and pepper to taste

In a food processor, blend together basil leaves, nuts, garlic, and cheese. Pour in oil slowly while still mixing. Stir in salt and pepper.

Pesto Chicken Pasta Casserole Recipe (5)

Easy Pesto Sauce Recipes:

We couldn’t get enough pesto sauce after trying this recipe, and we’re pretty sure you’ll feel the same way. Here are a few of our favorite pesto recipes, using both homemade and pre-made pesto sauce.

  • Pesto Chicken Florentine
  • Pesto Tortellini Bake
  • Pesto Potatoes
  • Noodles and Company Pesto Cavatappi Copycat
  • Easy Pesto Chicken Bake

Want even more recipe ideas that use already made chicken ?! Try these 45 Cold Chicken Recipes (Best Leftover Chicken Ideas)!

If you’re really feeling domestic, you can serve this with our Easy Homemade Rolls, our Caprese Salad, and our Famous Marshmallow Brownies for dessert!

Want even more pasta dinners?! Try our EASY 20 Minute Tuscan Pasta!

Speaking of Copycat Recipes…

Have you heard about our newest cookbook, Copycat Cooking?

We took over 100 of our favorite restaurant recipes and simplified them so that you can make them right at home!

Pesto Chicken Pasta Casserole Recipe (6)

Every recipe has a beautiful mouth-watering photo and has been picky-eater approved.

This cookbook includes copycat recipes from Wingers, Texas Roadhouse, Starbucks, Panera, Cheesecake Factory, Kneaders, and so much more.

We are so excited to share these recipes with you. Order your copy today!

Love cooking as much as we do? Join our FREE private Facebook Group: Six Sisters’ Dinner Club!

Pesto Chicken Pasta Casserole Recipe (7)

Serves: 10

Pesto Chicken Pasta Casserole Recipe

4.58 from 7 votes

Chicken, tomatoes, spinach, basil pesto, and cheese come together to make this fresh pasta bake.

Prep Time 20 minutes mins

Cook Time 40 minutes mins

Total Time 1 hour hr

PrintPin

Ingredients

  • 16 ounces penne pasta
  • 4 boneless skinless chicken breasts cooked and shredded, could also use rotisserie chicken
  • ½ cup milk
  • 4 cups shredded mozzarella cheese
  • 3 cups baby spinach
  • 1 15 ounce can diced tomatoes drained
  • 1 15 ounce jar alfredo sauce
  • ½ cup prepared pesto
  • ½ cup plain bread crumbs
  • ½ cup grated Parmesan cheese
  • 1 Tablespoon olive oil

Instructions

  • Preheat oven to 350 degrees F.

  • Cook pasta according to package directions, drain and set aside.

  • In a large mixing bowl, combine pasta, chicken, milk, mozzarella cheese, baby spinach, diced tomatoes, Alfredo sauce and pesto. Mix until well combined.

  • Spread mixture into a 9×13-inch baking pan sprayed with nonstick cooking spray.

  • In a small mixing bowl, combine bread crumbs, Parmesan cheese and olive oil.

  • Sprinkle crumb mixture on top of casserole.

  • Bake for 35-40 minutes, or until crumb topping is golden brown and casserole is heated through.

Notes

  • Make sure to rinse your pasta off in cold water after you boil it. This will keep it from sticking together when you’re trying to mix it with your other casserole ingredients.
  • Whole wheat pasta and gluten free pasta will work great for this recipe!
  • You can make your own pesto sauce and alfredo sauce, but canned sauce will work great as well.

Nutrition

Calories: 467 kcal · Carbohydrates: 41 g · Protein: 29 g · Fat: 20 g · Saturated Fat: 8 g · Cholesterol: 71 mg · Sodium: 581 mg · Potassium: 386 mg · Fiber: 2 g · Sugar: 3 g · Vitamin A: 1473 IU · Vitamin C: 3 mg · Calcium: 346 mg · Iron: 2 mg

Equipment

  • 9×13-inch Baking Pan

  • Large Mixing Bowl

  • Small Mixing Bowl

Recipe Details

Course: Main Course

Cuisine: American

Pesto Chicken Pasta Casserole Recipe (8)

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Pesto Chicken Pasta Casserole Recipe (9)

Join The Discussion

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  1. Julia Robison says:

    This makes a lot, can you freeze half for another meal?

  2. Cyd says:

    You can definitely freeze the other half for another meal. Be sure it's in an airtight container or freezer container covered well.

  3. Katie says:

    I agree, this recipe does make a lot, however, we eat leftovers at our house. We cook one day and eat leftovers the next day. So I'm always looking for recipes that is conducive to that. The two things I will do different the next time is add more Alfredo sauce so it will be creamier. I will add more pesto sauce. We hardly noticed any pesto and we all love pesto. I will definitely make this recipe again.

  4. Samantha bahtijar says:

    What's your favourite way of.cooking chicken For meals like this?

  5. Cyd says:

    We often just boil a whole bunch of chicken breasts at a time, then shred them. If you have an instant pot, you could cook them very fast.

  6. Beth says:

    This was delicious! Will definitely be making this again!

    Pesto Chicken Pasta Casserole Recipe (10)

  7. Jamie says:

    How much is equivalent to a serving size? It’s not specified on the nutrition info.

  8. Kim says:

    This was delicious but I thought I had the largest bowls available, and the ingredients didn't fit in my largest bowl . I had to mix it in a big pot . I used a slightly larger casserole than 13x9 to bake it in . I am mystified as to how others fit all of this in a 13x9. I recommend using the whole jar of pesto which is a bit more than half a cup.

    Pesto Chicken Pasta Casserole Recipe (11)

  9. Ashley says:

    Hi, are the nutrition facts for a serving, what is the serving size?

  10. K. Damon says:

    This was AMAZING! I didn't add the tomatoe or the spinich but instead added broccoli. It will be on my regular meal list now. If you love pesto then you will love this recipe!

    Pesto Chicken Pasta Casserole Recipe (12)

  11. Esther says:

    I used turkey leftovers, rather than chicken. Turned out well!

  12. Momma Cyd says:

    All of the nutrition facts are under the recipe card in the post for this recipe.

  13. Angela says:

    Any advice on how this would do if I prepared it the day before, refrigerated overnight, and baked it the next evening?

  14. Diane Kesler says:

    I did not have mozzarella the first time I made this and it was still great. I also add chopped up artichoke hearts... and the kids didn’t even notice. I imagine any veggies and leftover turkey or ham would be great in this dish as well. It is very versatile.

    Pesto Chicken Pasta Casserole Recipe (13)

  15. Kimmy Wright says:

    We love this casserole. I make it with gluten free noodles. Tonight I had some funions that needed eastern up, so we crumbled them in place of the bread crumbs. We have also eaten it cold is a pasta salad.

    Pesto Chicken Pasta Casserole Recipe (14)

  16. Momma Cyd says:

    You could make this (do not bake) and cover it well and stick it in the fridge. Then bake it when ready.

  17. Nikki Darling says:

    Yeah I had to use 2 pans bc it wouldnt all fit.

  18. Jill Alford says:

    This was delicious! Great flavor and easy to assemble. I used Italian style diced tomatoes because it was all I had but it worked well! I will definitely make this again. It makes a lot too which is great for my family of 5.

    Pesto Chicken Pasta Casserole Recipe (15)

  19. Kinsey says:

    My whole family loved this recipe. I only did one cup of mozarella and a bunch of parm. I also only put it in the oven for about 20 minutes. Next time I might add a little more alfredo. We used the pesto from Costco and it was fab. Super easy recipe!

  20. Debbie Banaszek says:

    Too many noodles! Use 8 oz of cooked penne and cut topping by 1/2.

    Pesto Chicken Pasta Casserole Recipe (16)

Pesto Chicken Pasta Casserole Recipe (17)

About The Author:

Momma Cyd

Cyd is the mom of the six sisters and joined the team early on to help out. She shares the best of the best recipes from her kitchen, as well as responds to all the questions and comments on every post.

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Pesto Chicken Pasta Casserole Recipe (2024)

FAQs

What is the ratio of pasta to pesto? ›

As a very rough guide, your pesto should weigh about 2/3 the weight of the dried pasta you are cooking. So, for a standard, single serving of 75g of dried pasta, we think that 50g of pesto is about right.

How to make pesto sauce better? ›

Add a pinch of salt if the basil tastes too bitter or the pesto needs more zing. Add more Parmesan if you'd like a creamier/cheesier pesto. If desired, you can thin out the pesto with more olive oil.

Should I add pasta water to pesto? ›

Reserve some pasta water.

The salty, starchy pasta water will loosen the pesto enough to make a light sauce over the pasta. Because of its salty, starchy quality, this water will make a more flavorful, thicker final pesto sauce than regular water would.

Should pesto be added to hot pasta? ›

Don't mix the pasta and pesto over heat: The basil pesto doesn't like any additional heat (other than from the warm pasta), or it can turn dark green/black and loose flavor. You should combine the pasta and pesto in a bowl or cold pot – off heat.

Do you warm up pesto before you put it over spaghetti? ›

PESTO SHOULD NEVER BE “COOKED”. If you cook Pesto Sauce, you change the make up of the fresh basil and cause it to turn darker in color. It is best to warm it up and use it at room temperature. If it needs to be thinned out, you can do so by adding a little water, chicken stock, cream or white wine.

How much pesto to use from a jar? ›

For pesto sauces, use about one jar of 5.6-ounce sauce for a 16-ounce package of pasta. The amount of pesto sauce needed for pasta per person would be about . 75 ounces of sauce for each 2 ounce (about 1 cup cooked) serving of pasta.

Should I put pesto on before or after cooking? ›

Just be aware that exposing pesto to too much heat for too long will change its flavour. Whenever possible, therefore, we add it right at the end of the cooking process to minimise any flavour loss.

How to use pesto from a jar? ›

What are some ways to use pesto sauce? Other than pairing it with pasta, pesto sauce is a great way to add flavoring to soups, dips, or vegetables. Add pesto sauce as a condiment on sandwiches or use it to make compound butter. Finally, adding pesto to scrambled eggs introduces bold flavoring to this simple dish.

What pasta is best for pesto? ›

Pesto Sauce

This fresh and fragrant pasta sauce is served uncooked, so choose a pasta shape that won't overwhelm it. Similar to oil-based sauces, pesto is served best with longer cuts of pasta, like the corkscrew shape of Fusilli. Pesto works best with Bucatini, Capellini, thinner Spaghettini, and Fettuccine.

Why isn't pesto sticking to pasta? ›

The secret to making it even stickier is to mix it with a little bit of the water you cooked your pasta in. This water is bursting with starch and acts as an emulsifier and a thickener, giving you the best possible chance of serving a restaurant-quality dish.

Why does my pesto pasta taste bland? ›

Why is my pesto bland? It's likely because you need to add more basil or salt. You want your pesto to taste slightly too salty - that way when it's mixed with pasta the dish won't be bland.

Why do chefs add pasta water to sauce? ›

Once the pasta is in the sauce, add pasta water. This is the most vital step in the process. Starchy pasta water doesn't just help thin the sauce to the right consistency; it also helps it cling to the pasta better and emulsify with the fat and cheese you're going to be adding.

How much pesto for one serving of pasta? ›

Ingredients US Metric 1x 2x
  1. 2 ounces spaghetti , or use your favorite pasta. ...
  2. 1 ½ tablespoons pesto -Use store-bought or homemade pesto.
  3. 1 to 2 tablespoons reserved pasta water.
  4. 2 tablespoons freshly shredded Parmesan cheese -plus more for topping.
Sep 1, 2021

Can you eat pesto straight from the jar? ›

Almost all the jarred pestos you find in the supermarket will have been pasteurised to not only ensure that they can last a long time unopened, but so they are perfectly safe to eat straight from the jar. There is no need to heat pesto, although too many people do.

Why should basil pesto not be heated? ›

Never heat the pesto before adding it to pasta. First, the heat will cook the basil, destroying its aroma. Second, if you use cheese (i.e., Parmigiano-Reggiano), it will clump.

What is the ratio formula for pasta? ›

For perfect pasta: Water to Pasta Ratio: Use 4-6 quarts of water per pound of dry pasta. 🍝💧 Boiling Time: Boil pasta for 8-12 minutes, depending on the type and desired doneness.

What is the recipe formula for pesto? ›

The basic ratio is 1:2:2:8 (1 part nuts, 2 parts oil, 2 parts grating cheese, 8 parts leaves or herbs), plus garlic, lemon, and salt and pepper to taste.

What is the ratio of liquid to pasta? ›

With cooking pasta, the quantity of water is key to preventing the pasta from overcrowding or clumping up in the pot. According to the experts at Eataly, the high-end Italian marketplace, a good rule of thumb for the ratio of water to pasta is 4 quarts of boiling water for each pound of pasta.

What should the pasta to meat ratio be? ›

One pound of meat makes enough sauce to dress a pound of pasta, which serves four to six people. You can easily scale up from there, and I think you probably should, because ragù makes excellent leftovers, and freezes well.

References

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